Plan a MiSeq i100 Run

Use the following instructions to plan a run for the MiSeq i100 Series systems in BaseSpace Sequence Hub.

  1. Select the Runs tab, and then select the New Run drop-down.

  2. Select Run Planning.

  3. In the Run Name field, enter a unique name of your preference to identify the current run. The run name can contain a maximum of 255 alphanumeric characters, spaces, dashes, and underscores.

  4. [Optional] Enter a description for the run. The run description can contain a maximum of 255 characters.

  5. Select your sequencing system as the instrument platform.

  6. Select one of the following analysis locations.

    • BaseSpace — Analyze sequencing data in the cloud.

    • Local — Analyze sequencing data on-instrument.

  7. Enter the number of cycles performed in each read:

    • Read 1 — Enter the number of cycles for Read 1.

    • Index 1 — Enter the number of cycles for the Index 1 (i7) primer.

    • Index 2 — Enter the number of cycles for the Index 2 (i5) primer.

    • Read 2 — Enter the number of cycles for Read 2.

  8. Select Next.

  9. Select your analysis application. Please note that MiSeq i100 Series only supports one analysis per planned run.

  10. [Optional] Enter a description for the configuration.

  11. Select a library prep kit or add a new custom library prep kit as follows.

    • Select Add Custom Library Prep Kit under the Library Prep Kit dropdown.

    • Enter the name, read types, default read cycles, and compatible index adapter kits for your custom library prep kit.

    • Select Create New Kit.

  12. Select an index adapter kit or add a new a custom index kits as follows. If you are using more than one library, the libraries must have the same index read lengths.

    • Select Add Custom Index Adapter Kit under the Index Adapter Kit dropdown.

    • Select a template type and enter the kit name, adapter sequences, index strategies, and index sequences. Make sure the second index (i5) adapter sequences are in forward orientation.

    • Select Create New Kit.

  13. If applicable to your application, select a reference genome.

  14. Select Next to configure secondary analysis settings.

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