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Important information for MiSeq, MiniSeq, NextSeq500/550 and HiSeq users

Owners of these instruments need to take action in order to continue to use BaseSpace and other cloud services as soon as possible.

Background

Early versions of our instruments run Windows 7, which does not support modern encryption stanards, such as TLS 1.2. The encryption methods they support by default, TLS1.0 and TLS1.1 rely on the SHA-1 algorithm which is no longer considered secure. Cloud providers, such as Amazon and Microsoft are moving away from supporting these older ciphers, and we will be unable to support them from June 2023. While this change significantly improves our security, we it also means that these older instruments will not be able to connect or send data to our cloud services:
  • BaseSpace Sequence Hub
  • Illumina Connected Analytics
  • Checking and installing software updates online
  • Run monitoring through myIllumina
MiSeq, MiniSeq and NextSeq500/550 all have sofware updates available that install Windows 10, and support TLS 1.2 and above. You need to update your instruments before June to continue to use BaseSpace and other illumina cloud serivices. See the table below for details on which versions are affected.
**HiSeq instruments were discontinued in 2018. We do not have an update option that will allow them to continue to use cloud services. **
Instrument Type
Affected Versions
Recommended Version
NextSeq
all before 4.0
4.0 or later
MiSeq
all before 4.0
4.0 or later
MiSeqDx (RUO mode)
all before 4.0
4.1 or later
MiniSeq
all before 2.0
2.2 or later
Last modified 16d ago